Treatment-Resistant Depression (TRD) is a special class of depressive disorders that do not respond to medications or therapy alone. When depression persists despite normal treatment, those suffering become disillusioned and may blame themselves for lack of response. Suicidal ideation and substance use are all too common responses to such suffering and complicate the lives of the affected.

Combatting TRD requires multimodal treatment including medication augmentation strategies, neurostimulation, intensive psychotherapies, and behavioral activation (exercise, social activity, work, and volunteerism). Our coordinated specialty care program, and affiliation with Houston Methodist Hospital’s psychiatry department  allows for second opinion and rapid referral for neurostimulation services if deemed appropriate.