Treatment-Resistant Anxiety Spectrum Disorders develop when symptoms persist despite evidence-based medication and therapy. Multimodal treatments are needed including higher doses of medications, augmentation strategies, neurostimulation, and intensive psychotherapies, and behavioral activation (exercise, social activity, work, and volunteerism). Our coordinated specialty care program, and affiliation with Houston Methodist Hospital’s psychiatry department  allows for second opinion and rapid referral for neurostimulation services if deemed appropriate.